TABLE 3.
Biological risk factors |
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Components of AHEI-2010 | LDL-C (n = 1743)2 | HDL-C (n = 1743)2 | TGs (n = 1743)2 | HbA1c (n = 1743)2 | hsCRP (n = 1743)2 | Creatinine (n = 1743)2 | SBP (n = 1122)3 | DBP (n = 1122)3 |
AHEI-2010 score | −0.024 | 0.029 | −0.036 | −0.015 | −0.014 | −0.011 | −0.058 | −0.053 |
Vegetables | −0.009 | −0.040 | −0.020 | −0.023 | 0.019 | 0.019 | −0.077* | −0.089** |
Fruit | −0.004 | −0.008 | −0.016 | 0.034 | −0.009 | −0.027 | −0.042 | 0.003 |
Whole grains | −0.063** | 0.038 | −0.065** | −0.005 | −0.023 | −0.004 | −0.055 | −0.085** |
Nuts and legumes | −0.011 | −0.010 | −0.007 | −0.022 | 0.022 | 0.007 | −0.047 | −0.045 |
Alcohol | 0.042 | 0.096*** | 0.022 | −0.016 | −0.010 | −0.040 | 0.055 | 0.041 |
Long-chain n–3 PUFAs | 0.063** | −0.004 | 0.017 | 0.037 | 0.034 | 0.007 | −0.011 | 0.002 |
PUFAs, % of energy | −0.015 | 0.009 | −0.023 | −0.009 | 0.021 | −0.005 | −0.072* | −0.049 |
Low sugar-sweetened beverage and juice intake | −0.043 | 0.024 | −0.032 | −0.042 | −0.023 | 0.029 | −0.025 | −0.033 |
Low red and processed meat intake | −0.044 | 0.004 | −0.023 | −0.019 | −0.043 | −0.006 | −0.011 | 0.015 |
Low sodium intake | −0.039 | −0.008 | −0.014 | 0.008 | −0.065** | −0.022 | 0.048 | 0.034 |
The mean ± SD time after dietary assessment was 6.6 ± 1.9 y. Duplicate controls were excluded. TGs, HbA1c, hsCRP, and creatinine were log-transformed. *P < 0.05, **P < 0.01, ***P < 0.001. AHEI, Alternative Healthy Eating Index; CVD, cardiovascular disease; DBP, diastolic blood pressure; HbA1c, glycated hemoglobin; HDL-C, HDL cholesterol; hsCRP, high-sensitivity C-reactive protein; LDL-C, LDL cholesterol; SBP, systolic blood pressure.
Correlations were adjusted for disease status (case or control), age at interview (y), sex (male or female), dialect group (Hokkien or Cantonese), year of interview (1993–1995 or 1996–1998), year blood was collected, total energy intake (kcal/d), level of education (none, primary, or secondary and above), cigarette smoking (never; ex-smoker; current smoker: <13 or ≥13 cigarettes/d), physical activity (0 h/wk of moderate and strenuous activity, <4 h/wk of moderate or <2 h/wk of strenuous activity, ≥4 h/wk of moderate or ≥2 h/wk of strenuous activity), BMI (kg/m2; <18.5, 18.5 to <23, 23 to <27.5, or ≥27.5), with the exclusion of 341 participants with a history of physician-diagnosed diabetes.
Correlations were adjusted as in footnote 2, with further exclusion of 621 participants with a history of physician-diagnosed hypertension.