Table 3.
Determinants of the primary efficacy end point (halving of initial eGFR or dialysis initiation)
| Determinant | B | SEM | Exp(B) (95% CI) | P Value |
|---|---|---|---|---|
| Arm (KD versus LPD) | −2.29 | 0.35 | 0.10 (0.05 to 0.20) | <0.001 |
| Body mass index | −4.28 | 1.46 | 0.01 (0.00 to 0.24 | 0.003 |
| ACEI/ARB (yes versus no) | −0.68 | 0.29 | 0.51 (0.28 to 0.90) | 0.02 |
| CRP | 1.55 | 0.38 | 4.72 (2.25 to 9.90) | <0.001 |
| eGFR | −5.79 | 0.74 | <0.01 (<0.01 to 0.01) | <0.001 |
Backward stepwise Cox regression: variables present in the last step. Significant predictors of outcome5 were considered at the first step: ACEI/ARB, age, body mass index, CRP, diet, initial eGFR, sex, midarm muscular circumference, mean arterial pressure, primary renal disease, proteinuria, serum albumin, serum bicarbonate, serum calcium, serum phosphate, and urinary creatinine. B, regression coefficient; SEM, standard error of the mean; Exp(B), hazard ratio.