Table 3.
Comparison of biopsy characteristics
| Variable and Banff score (where applicable) | TRI+ (n=41; %) | TRI− (n=82; %) | P Value |
|---|---|---|---|
| Type of biopsy | |||
| Surveillance | 14 (34.1) | 20 (24.4) | 0.35 |
| Indicative | 27 (65.9) | 62 (75.6) | |
| g Score | |||
| 0a | 26 (63.41) | 58 (70.73) | 0.54 |
| 1 | 8 (19.51) | 18 (21.95) | |
| 2 | 6 (14.63) | 5 (6.10) | |
| 3 | 1 (2.44) | 1 (1.22) | |
| Mean g score | 0.56±0.84 | 0.38±0.66 | 0.19 |
| ptc Score | |||
| 0a | 31 (75.61) | 68 (82.93) | 0.47 |
| 1 | 7 (17.07) | 7 (8.54) | |
| 2 | 3 (7.32) | 7 (8.54) | |
| 3 | 0 | 0 | |
| Mean ptc score | 0.32±0.61 | 0.28±0.62 | 0.73 |
| MI score (ptc + g) | |||
| 0a | 20 (48.78) | 53 (64.63) | 0.14 |
| 1 | 13 (31.71) | 15 (18.29) | |
| 2 | 5 (12.20) | 7 (8.54) | |
| 3 | 0 | 5 (6.10) | |
| 4 | 2 (4.88) | 2 (2.44) | |
| 5 | 1 (2.44) | 0 | |
| 6 | 0 | 0 | |
| Mean MI score | 0.85±1.22 | 0.64±1.04 | 0.32 |
| cg Score | |||
| 0a | 35 (85.37) | 76 (92.68) | 0.33 |
| 1 | 4 (9.76) | 3 (3.66) | |
| 2 | 1 (2.44) | 1 (1.22) | |
| 3 | 1 (2.44) | 2 (2.44) | |
| Mean cg score | 0.22±0.61 | 0.13±0.54 | 0.43 |
| t Score | |||
| 0a | 29 (70.73) | 55 (67.07) | 0.73 |
| 1 | 9 (21.95) | 18 (21.95) | |
| 2 | 2 (4.88) | 6 (7.32) | |
| 3 | 1 (2.44) | 3 (3.66) | |
| Mean t score | 0.39±0.70 | 0.48±0.79 | 0.56 |
| i Score | |||
| 0a | 32 (78.05) | 66 (80.49) | 0.94 |
| 1 | 4 (9.76) | 8 (9.76) | |
| 2 | 4 (9.76) | 5 (6.10) | |
| 3 | 1 (2.44) | 3 (3.66) | |
| Mean i score | 0.37±0.77 | 0.33±0.76 | 0.82 |
| ct Score | |||
| 0a | 14 (34.15) | 28 (34.15) | 0.84 |
| 1 | 14 (34.15) | 40 (48.78) | |
| 2 | 9 (21.95) | 8 (9.76) | |
| 3 | 4 (9.76) | 5 (6.40) | |
| Mean ct score | 1.07±0.98 | 0.88±0.82 | 0.25 |
| ci Score | |||
| 0a | 14 (34.15) | 28 (34.15) | 0.84 |
| 1 | 14 (34.15) | 40 (48.78) | |
| 2 | 9 (21.95) | 8 (9.76) | |
| 3 | 4 (9.76) | 5 (6.40) | |
| Mean ci score | 1.07±0.98 | 0.88±0.82 | 0.25 |
| v Score | |||
| 0a | 41 (100.0) | 76 (92.68) | 0.18 |
| 1 | 0 | 4 (4.88) | |
| 2 | 0 | 2 (2.44) | |
| 3 | 0 | 0 | |
| Mean v score | 0 | 0.10±0.38 | NA |
| cv Score | |||
| 0a | 14 (34.15) | 28 (34.15) | |
| 1 | 15 (36.59) | 34 (41.46) | |
| 2 | 10 (24.39) | 17 (20.73) | |
| 3 | 2 (4.88) | 3 (3.66) | |
| Mean cv score | 1.00±0.89 | 0.94±0.84 | 0.76 |
| PTCBMML | |||
| Yes | 5 (13.16)b | 11 (14.67)c | 0.95 |
| No | 33 (86.84) | 64 (85.33) | |
| C4d | |||
| 0a | 23 (56.10) | 40 (48.78) | 0.57 |
| 1 | 13 (31.71) | 23 (28.05) | |
| 2 | 4 (9.76) | 10 (12.20) | |
| 3 | 1 (2.44) | 9 (10.98) | |
| Evidence of GN | |||
| Yes | 10 (24.4) | 25 (30.5) | 0.62 |
| No | 31 (75.6) | 57 (69.5) | |
| BK nephropathy | |||
| Yes | 2 (4.9) | 5 (6.1) | 0.99 |
| No | 39 (95.1) | 77 (93.9) |
g, Glomerulitis; cg, chronic glomerulopathy; t, tubulitis; i, interstitial inflammation; ct, tubular atrophy; ci, interstitial fibrosis; v, vasculitis; NA, non-applicable; cv, chronic vascular; PTCBMML, peritubular capillary basement membrane multilayering; BK, BK virus.
a
Comparator group.
b
Data available in 38 of 41 patients.
c
Data available in 75 of 82 patients.