Table 1.
Baseline characteristics
| HBeAg Pos (n=237) | HBeAg Neg (n=421) | P value | |
|---|---|---|---|
| Age (yr) | 40.4 (18.2–80.2) | 50.1 (21.1–83.0) | <0.001 |
| Male, n(%) | 147 (62.0) | 280 (66.5) | 0.25 |
| Race, n(%) | 0.018 | ||
| Asian | 186 (78.5) | 362 (86.0) | |
| Black | 13 (5.5) | 17 (4.0) | |
| White | 30 (12.7) | 25 (5.9) | |
| Other | 8 (3.4) | 17 (4.0) | |
| Country of Birth, n(%) | 0.0001 | ||
| Outside US | 143 (60.3) | 259 (61.5) | |
| US | 38 (16.0) | 27 (6.4) | |
| Unknown | 56 (23.6) | 135 (32.1) | |
| Cirrhosis, n(%) | 23 (9.7) | 38 (9.0) | 0.25 |
| Hepatic Decompensation, n(%) | 3 (1.3) | 8 (1.9) | 0.75 |
| Listed for Liver Transplant, n(%) | 1 (0.4) | 2 (0.5) | 1 |
| Undetectable HBV DNA, n(%) | 3 (1.3) | 8 (1.9) | 0.75 |
| Normal ALT ( ALT < 30 for men and < 19 for women), n(%) | 19 (8.0) | 52 (12.4) | 0.085 |
| Normal ALT ( ALT < 40 for men and women), n(%) | 55 (23.2) | 146 (34.7) | 0.002 |
| HBV DNA (Log10 IU/ml) | 7.4 (2.0–10.2) | 5.2 (1.9–8.7) | <0.001 |
| ALT (U/L) | 71.0 (15.0–3286) | 55.0 (6.0–1783) | <0.001 |
| AST (U/L) | 46.0 (4.5–1334) | 39.0 (13.0–1385) | <0.01 |
| Albumin (g/dL) | 4.3 (2.7–5.1) | 4.4 (1.4–5.1) | <0.01 |
| Total Bilirubin (mg/dL) | 0.7 (0.0–13.4) | 0.7 (0.0–9.1) | 0.79 |
| Creatinine (mg/dL) | 0.9 (0.4–8.2) | 0.9 (0.5–13.4) | 0.67 |
| INR | 1.0 (0.9–2.5) | 1.1 (0.8–3.1) | 0.25 |
| Platelet Count (× 10^3/uL) | 203.0 (46.0–522.0) | 201.5 (43.0–1051) | 0.46 |