Table 3.

Significant between-group differences in activity for conditioned responses to CS + vs CS− during extinction (n = 75)

Group comparison	Brain region	PFWE-SVC	Z-score	x	y	z
HC<(DBD-p and DBD-d)	ACC	0.014	3.9	2	22	32
	Left insula	0.026	3.8	−40	−8	10
	Right insula	0.048	3.6	40	−2	−10
HC<DBD-p	ACC	0.018	3.9	2	20	28
HC<DBD-d	Right insula	0.026	3.8	40	−2	−10
	ACC	0.058	3.5	6	14	40

CS+, conditioned stimulus followed by unconditioned stimulus; CS−, conditioned stimulus never followed by unconditioned stimulus; P_FWE-SVC, family wise error small volume correction for multiple comparison; DBD-d, desisters; DBD-p, persisters; HC, controls, ACC, anterior cingulate cortex.