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. 2015 Jun 5;11(7):1027–1035. doi: 10.1093/scan/nsv067

Table 3.

Significant between-group differences in activity for conditioned responses to CS + vs CS− during extinction (n = 75)

Group comparison Brain region PFWE-SVC Z-score x y z
HC<(DBD-p and DBD-d) ACC 0.014 3.9 2 22 32
Left insula 0.026 3.8 −40 −8 10
Right insula 0.048 3.6 40 −2 −10
HC<DBD-p ACC 0.018 3.9 2 20 28
HC<DBD-d Right insula 0.026 3.8 40 −2 −10
ACC 0.058 3.5 6 14 40

CS+, conditioned stimulus followed by unconditioned stimulus; CS−, conditioned stimulus never followed by unconditioned stimulus; PFWE-SVC, family wise error small volume correction for multiple comparison; DBD-d, desisters; DBD-p, persisters; HC, controls, ACC, anterior cingulate cortex.