Table 2.

Classification of infertility risk induced by chemotherapy in females.

CHEMOTHERAPY TREATMENT	DEGREE OF RISK
Hematopoietic stem cell transplantation and total body irradiation Radiotherapy to a field including the ovaries	High risk >80%
CAF, CMF, CEF x6 30–39 years of age ACx4 >40 years of age	Intermediate risk
ABVD,CHOP,CVP,AML, ALL CAF, CMF, CEF x6 <30 years of age ACx4 <40 years of age	Lower Risk (<20%)
Vincristine Methotrexate Fluorouracil	Very Low or No Risk
Taxanes Irinotecan Oxaliplatin Monoclonal antibodies Tyrosine kinase inhibitors	Unknown Risk

Abbreviations: C, cyclophosphamide 600–1200 mg/m²; A, adriamycin 25–60 mg/m²; F, fluorouracil 600 mg/m²; E, epirubicin 60 mg/m²; M, methotrexate 40 mg/m²; B, bleomycin 10 U/m²; V, vinblastine 6 mg/m²; D, dacarbazine 375 mg/m²; V (O), vincristine 1.2 mg/m²–2 mg; P, prednisolone 40 mg/m²; H, hydroxydaunorubicin 50 mg/m².