Table 2.

C3 analogs of ∆8-THC and ∆9-THC.

#		CB	NAME	CB1 KI (nM)	CB2 KI (nM)	FUNCTIONAL	REF
54		Δ8-THC	AMG-41	0.44 ± 0.07	0.86 ± 0.16		94
55		Δ8-THC		1.5 ± 0.2	11.5 ± 3.4		138
56		Δ8-THC	AMG-36	0.45 ± 0.07	1.92 ± 0.4		139
57		Δ8-THC		18.4 ± 2.1	23.5 ± 4.1		138
58		Δ8-THC		13.6 ± 2.4	143 ± 31.5		138
59		Δ8-THC		3.9 ± 0.5	4.9 ± 0.7		138
60		Δ8-THC		0.32 ± 0.08	0.52 ± 0.17		135
61		Δ8-THC		0.52 ± 0.11	0.22 ± 0.06		139
62		Δ8-THC		32.3 ± 4.0	19.7 ± 2.7		139
63		Δ8-THC		56.9 ± 6.8	257 ± 41		139