TABLE 6.
Multivariable analysis of predictive factors in isolated regional recurrence and recurrence-free survival.
| Characteristics | Isolated regional failure
|
RFS
|
||
|---|---|---|---|---|
| RR (95% CI) | p value | RR (95% CI) | p value | |
| Tobacco use | .74 | |||
| Never smoker | Reference | |||
| Past or current smoker | 1.07 (0.7–1.65) | |||
| Alcohol use | .067 | |||
| Never drinker | Reference | |||
| Past or current drinker | 0.67 (0.43–1.03) | |||
| Pathologic T classification | .8 | .0016 | ||
| T1–T2 | Reference | Reference | ||
| T3–T4 | 0.9 (0.4–2.03) | 1.98 (1.3–3.03) | ||
| Primary tumor site | .05 | |||
| Maxillary alveolus | Reference | |||
| Hard palate | 2.14 (1–4.56) | |||
| Elective neck dissection | .09 | .025 | ||
| Yes | Reference | Reference | ||
| No | 3.43 (0.81–14.52) | 2.05 (1.09–3.82) | ||
| Surgical margins | .27 | .61 | ||
| Negative | Reference | Reference | ||
| Positive | 1.75 (0.83–3.69 | 1.16 (0.66–2.04) | ||
| Adjuvant radiotherapy | .37 | .36 | ||
| No | Reference | Reference | ||
| Yes | 0.57 (0.16–1.97) | 0.75 (0.41–1.38) | ||
Abbreviations: RFS, recurrence-free survival; RR, risk ratio; 95% CI, 95% confidence interval.
The figures in bold indicate statistical significance.