Table 1. Effects of gender on haemorheological parameters in SS and SC patients.
SS | SC | |||
---|---|---|---|---|
Males (n = 122) | Females (n = 145) | Males (n = 67) | Females (n = 71) | |
HbF (%) | 7.5 ± 6.4 | 13.2 ± 11.8*** | 2.7 ± 3.1 | 3.1 ± 5.1 |
Hydroxycarbamide treatment (%) | 25.6 | 23.6 | 0 | 0 |
Haematocrit | 0.23 ± 0.05 | 0.25 ± 0.04* | 0.32 ± 0.03 | 0.31 ± 0.02 |
Blood viscosity (cP) | 5.15 ± 1.32 | 5.34 ± 1.37 | 6.64 ± 1.40 | 6.94 ± 1.30 |
RBC deformability (3 Pa, a.u.) | 0.18 ± 0.08 | 0.21 ± 0.06** | 0.18 ± 0.03 | 0.18 ± 0.04 |
RBC deformability (30 Pa, a.u.) | 0.38 ± 0.12 | 0.43 ± 0.10*** | 0.44 ± 0.06 | 0.45 ± 0.07 |
RBC aggregates strength (s-1) | 303 ± 155 | 274 ± 136 | 298 ± 143 | 288 ± 108 |
Means ± SD. HbF, foetal haemoglobin. Significant difference between Males and Females:
*p < 0.05
**p < 0.01
***p < 0.001