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. 2016 Jun 29;11(6):e0158182. doi: 10.1371/journal.pone.0158182

Table 1. Effects of gender on haemorheological parameters in SS and SC patients.

SS SC
Males (n = 122) Females (n = 145) Males (n = 67) Females (n = 71)
HbF (%) 7.5 ± 6.4 13.2 ± 11.8*** 2.7 ± 3.1 3.1 ± 5.1
Hydroxycarbamide treatment (%) 25.6 23.6 0 0
Haematocrit 0.23 ± 0.05 0.25 ± 0.04* 0.32 ± 0.03 0.31 ± 0.02
Blood viscosity (cP) 5.15 ± 1.32 5.34 ± 1.37 6.64 ± 1.40 6.94 ± 1.30
RBC deformability (3 Pa, a.u.) 0.18 ± 0.08 0.21 ± 0.06** 0.18 ± 0.03 0.18 ± 0.04
RBC deformability (30 Pa, a.u.) 0.38 ± 0.12 0.43 ± 0.10*** 0.44 ± 0.06 0.45 ± 0.07
RBC aggregates strength (s-1) 303 ± 155 274 ± 136 298 ± 143 288 ± 108

Means ± SD. HbF, foetal haemoglobin. Significant difference between Males and Females:

*p < 0.05

**p < 0.01

***p < 0.001