Table 3. Unadjusted and adjusted odds ratio (OR) for wound infection by cutoffs of 25-Hydroxyvitamin D and 1,25-Dihydroxyvitamin D.
| Vitamin D | N | Primary Endpoint N (%) | Model 1 OR (95% CI) | Model 2 OR (95% CI) | Model 3 OR (95% CI) | Model 4 OR (95% CI) |
|---|---|---|---|---|---|---|
| 25OHD | ||||||
| <30 nmol/l | 838 | 58 (6.9) | 1.77 (0.96–3.28) | 1.94 (1.03–3.65) | 1.83 (0.97–3.47) | 1.62 (0.87–3.20) |
| 30–49.9 nmol/l | 1183 | 56 (4.7) | 1.15 (0.62–2.14) | 1.28 (0.68–4.41) | 1.30 (0.69–2.46) | 1.28 (0.67–2.43) |
| 50–74.9 nmol/l | 850 | 47 (5.5) | 1.36 (0.72–2.55) | 1.54 (0.81–2.93) | 1.60 (0.84–3.07) | 1.56 (0.81–3.02) |
| 75–100 nmol/l | 318 | 13 (4.1) | 1.0 (reference) | 1.0 (reference) | 1.0 (reference) | 1.0 (reference) |
| >100 nmol/l | 151 | 12 (7.9) | 2.01 (0.72–4.51) | 1.90 (0.82–4.36) | 1.91 (0.83–4.43) | 1.78 (0.76–4.17) |
| 1,25(OH)2D | ||||||
| Lowest Quintile (<31.5 pmol/l) | 668 | 62 (9.3) | 3.97 (1.74–4.18) | 3.37 (1.98–5.71) | 3.11 (1.82–5.29) | 2.57 (1.47–4.49) |
| Second Lowest Quintile (31.5–49.0 pmol/l) | 668 | 43 (6.4) | 2.23 (0.93–2.43) | 2.07 (1.20–3.59) | 2.02 (1.16–3.51) | 1.85 (1.05–3.25) |
| Intermediate Quintile (49.1–63.0 pmol/l/l) | 668 | 30 (4.5) | 1.49 (0.84–2.66) | 1.42 (0.79–2.54) | 1.38 (0.77–2.48) | 1.36 (0.75–2.45) |
| Second Highest Quintile (63.1–81.0 pmol/l) | 668 | 31 (4.6) | 1.58 (0.89–2.80) | 1.55 (0.87–2.75) | 1.49 (0.84–2.65) | 1.48 (0.82–2.65) |
| Highest Quintile (>81.0 pmol/l) | 668 | 20 (3.0) | 1.0 (reference) | 1.0 (reference) | 1.0 (reference) | 1.0 (reference) |
Model 1: adjusted for age and gender
Model 2: adjusted as in model 1 and for body mass index, redo, operation priority, and type of surgery
Model 3: adjusted as in model 2 and for left ventricular ejection fraction, NYHA function class, and EuroSCORE
Model 4: adjusted as in model 3 and for kidney function (eGFR), inflammatory process (CRP), and diabetes mellitus