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. 2016 Jun 29;11(6):e0156134. doi: 10.1371/journal.pone.0156134

Table 3. Clinical parameter changes after treatment and at follow-up.

POST vs BASELINE FOLLOW-UP vs BASELINE
Parameter Within groups Between groups Within groups Between groups
rtACS Sham rtACS Sham
mean ±SEM p mean ±SEM p mean ±SEM p mean ±SEM p mean ±SEM p mean ±SEM p
High Resolution Perimetry
Detection accuracy in whole visual field, % 23.96 ±10.1 <0.001 2.53 ±2.75 0.256 21.43 ±10.46 0.011 24.98 ±11.01 0.006 0.28 ±3.34 0.482 24.70 ±11.51 0.033
Detection accuracy in defective visual field sectors, % 59.86 ±13.44 <0.001 34.83 ±5.30 <0.001 25.03 ±14.44 0.131 61.29 ±16.14 <0.001 30.72 ±5.96 <0.001 30.56 ±17.21 0.078
Detection accuracy within 5° visual field, % 63.24 ±55.67 0.075 1.13 ±3.90 0.472 62.11 ±55.80 0.170 66.74 ±51.45 0.081 -0.96 ±2.46 0.500 67.71 ±51.51 0.146
Fixation accuracy (%) 12.20 ±8.62 0.015 5.66 ±3.55 0.016 6.54 ±9.32 0.427 30.48 ±19.77 0.076 6.08 ±2.91 0.013 24.40 ±19.98 0.390
False positive reactions in % 33.75 ±9.97 0.003 22.73 ±18.10 0.237 11.01 ±20.67 0.076 50.18 ±12.92 <0.001 46.70 ±22.74 0.034 3.49 ±26.15 0.134
RT whole visual field (ms) 2.13 ±0.87 0.022 1.30 ±1.19 0.086 0.86 ±1.47 0.338 1.49 ±0.89 0.084 0.59 ±1.30 0.383 0.90 ±1.58 0.242
RT in defective visual field sectors (ms) 2.03 ±0.96 0.063 1.48 ±1.04 0.075 0.55 ±1.42 0.452 1.61 ±0.87 0.086 2.22 ±1.62 0.127 -0.60 ±1.84 0.485
RT within 5° visual field (ms) 3.46 ±1.00 0.001 2.74 ±1.43 0.013 0.72 ±1.74 0.437 3.41 ±1.27 0.006 2.44 ±1.51 0.052 0.97 ±1.97 0.383
Static Perimetry
Foveal threshold (dB) -1.72 ±4.03 0.367 0.05 ±5.80 0.297 -1.77 ±7.06 0.402 1.13 ±3.00 0.368 -7.52 ±4.22 0.174 8.65 ±5.18 0.151
Mean threshold (whole visual field, dB) 22.38 ±10.67 0.003 3.72 ±5.00 0.272 18.65 ±11.78 0.063 34.97 ±18.52 0.001 2.14 ±4.59 0.486 32.83 ±19.08 0.010
Fixation accuracy in static perimetry, % 0.93 ±3.36 0.373 2.82 ±2.62 0.129 -1.89 ±4.26 0.206 10.69 ±10.19 0.197 -4.00 ±3.62 0.205 14.70 ±10.81 0.192
Kinetic Perimetry
Mean eccentricity (°) 11.62 ±6.27 0.035 6.40 ±5.13 0.063 5.22 ±8.10 0.406 2.51 ±5.45 0.426 4.47 ±4.37 0.159 -1.96 ±6.99 0.285
Mean visual field size (square degree) 27.27 ±16.44 0.036 20.47 ±15.89 0.040 6.80 ±22.90 0.385 11.23 ±11.86 0.413 9.06 ±6.90 0.184 2.17 ±13.72 0.29
Visual acuity
Uncorrected near vision -0.014 ±0.016 0.267 -0.082 ±0.020 <0.001 0.068 ±0.026 0.012 -0.066 ±0.017 0.001 -0.068 ±0.025 0.002 0.003 ±0.029 0.370
Uncorrected far vision -0.039 ±0.023 0.067 -0.032 ±0.019 0.032 -0.007 ±0.030 0.371 -0.020 ±0.025 0.257 -0.032 ±0.019 0.064 0.012 ±0.031 0.226

For cases with binocular lesions values for both eyes were averaged. Results are given as mean and standard error mean (SEM).