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. 2016 Aug 15;137:178–187. doi: 10.1016/j.neuroimage.2016.05.031

Table 1.

Clinical details. UPDRS = Part III motor score of the United Parkinson's Disease Rating Scale. The first symptoms for patients 8 and 12 were not available.

Case Age Disease Duration UPDRS Off (III) UPDRS
On (III)
First symptom Reasons for surgery Daily medication (mg/d)
1 58 10 42 20 Leg cramp Tremor Trihexyphenidyl 3 Levodopa 600 Rasagiline 1 Amantadine 100
2 62 10 20 8 Left side tremor & bradykinesia On/off fluctuations, tremor & impulse control disorder Levodopa 1000 Trihexyphenidyl 6
3 61 4 37 15 Left side tremor Tremor Amantadine 200 Levodopa 750 Entacapone 1000
4 65 15 51 21 Left hand tremor Freezing Amantadine 200 Levodopa 400 Ropinirole 12
5 44 10 33 7 Left hand tremor Motor fluctuations, dyskinesia Amantadine 200 Ropinirole 24 Rasagiline 1 Levodopa 600 Apomorphine 4.5 mg/h
6 42 9 60 42 Loss of dexterity Bradykinesia, dystonia, freezing Amantadine 400 Levodopa 600
7 51 9 56 12 Tremor Motor fluctuations, dyskinesia Apomorphine 4 Levodopa 1500 Entacapone 600
8 43 10 36 6 Motor fluctuations Levodopa 600 Ropinirole 2
9 59 16 54 9 Loss of dexterity Dyskinesia, painful cramps Levodopa 100 Apomorphine 5 mg/h Rotigotine 4
10 69 10 34 12 Shuffling gait Motor fluctuations, bradykinesia Levodopa 800 Amantadine 100
11 53 7 25 5 Loss of dexterity Dyskinesia, bradykinesia Levodopa 800 Entacapone 800 Rasagiline 1
12 67 12 25 9 Off periods, & dyskinesia Levodopa 950 Amantadine 100 Pramipexole 2.25
13 63 13 32 18 Dragging of left leg Stiffness Levodopa 700 Entacapone 1000 Ropinirole 8 Quetiapine 25 Clonazepam 0.5