Table 1.
Case | Age | Disease Duration | UPDRS Off (III) | UPDRS On (III) |
First symptom | Reasons for surgery | Daily medication (mg/d) |
---|---|---|---|---|---|---|---|
1 | 58 | 10 | 42 | 20 | Leg cramp | Tremor | Trihexyphenidyl 3 Levodopa 600 Rasagiline 1 Amantadine 100 |
2 | 62 | 10 | 20 | 8 | Left side tremor & bradykinesia | On/off fluctuations, tremor & impulse control disorder | Levodopa 1000 Trihexyphenidyl 6 |
3 | 61 | 4 | 37 | 15 | Left side tremor | Tremor | Amantadine 200 Levodopa 750 Entacapone 1000 |
4 | 65 | 15 | 51 | 21 | Left hand tremor | Freezing | Amantadine 200 Levodopa 400 Ropinirole 12 |
5 | 44 | 10 | 33 | 7 | Left hand tremor | Motor fluctuations, dyskinesia | Amantadine 200 Ropinirole 24 Rasagiline 1 Levodopa 600 Apomorphine 4.5 mg/h |
6 | 42 | 9 | 60 | 42 | Loss of dexterity | Bradykinesia, dystonia, freezing | Amantadine 400 Levodopa 600 |
7 | 51 | 9 | 56 | 12 | Tremor | Motor fluctuations, dyskinesia | Apomorphine 4 Levodopa 1500 Entacapone 600 |
8 | 43 | 10 | 36 | 6 | Motor fluctuations | Levodopa 600 Ropinirole 2 | |
9 | 59 | 16 | 54 | 9 | Loss of dexterity | Dyskinesia, painful cramps | Levodopa 100 Apomorphine 5 mg/h Rotigotine 4 |
10 | 69 | 10 | 34 | 12 | Shuffling gait | Motor fluctuations, bradykinesia | Levodopa 800 Amantadine 100 |
11 | 53 | 7 | 25 | 5 | Loss of dexterity | Dyskinesia, bradykinesia | Levodopa 800 Entacapone 800 Rasagiline 1 |
12 | 67 | 12 | 25 | 9 | Off periods, & dyskinesia | Levodopa 950 Amantadine 100 Pramipexole 2.25 | |
13 | 63 | 13 | 32 | 18 | Dragging of left leg | Stiffness | Levodopa 700 Entacapone 1000 Ropinirole 8 Quetiapine 25 Clonazepam 0.5 |