Table 1. Key parameters used in model.
The parameters were based on the Home HTC study and other literature. For parameters with varying estimates, we chose values that best fit our data.
| Model Parameter | Value [Range] | Reference |
|---|---|---|
| Duration of Disease | ||
| By CD4 Count | ||
| Acute | 0·25 year [0·2, 0·25] | Johnson et al.16 |
| >500 cells/µL | 1·88 years | Celum et al., Baeten et al.17,18 |
| 500 to 350 cells/µL | 1·22 years | Celum et al., Baeten et al.17,18 |
| 350 to 200 cells/µL | 5·90 years | Celum et al., Baeten et al.17,18 |
| ≤200 cells/µL | 1·96 years (95% CI: 3·0–4·3 years) |
Badri et al.19 |
| By HIV Viral Load | ||
| Acute | 0·25 year | Johnson et al.16 |
| <1,000 copies/mL | 3·13 years | Celum et al., Baeten et al.17,18 |
| 1,000–10,000 copies/mL | 1·99 years | Celum et al., Baeten et al.17,18 |
| 10,000–50,000 copies/mL | 4·40 years | Celum et al., Baeten et al.17,18 |
| >50,000 copies/mL | 1·44 years | Estimated |
| Costs | ||
| Annual Home HTC with | HIV-positive: $28·06 per person | Smith et al.20 |
| Community Care Workers | HIV-negative: $8·22 per person |