Skip to main content
. Author manuscript; available in PMC: 2016 Dec 1.
Published in final edited form as: Leukemia. 2015 Nov 20;30(6):1422–1425. doi: 10.1038/leu.2015.320

Figure 1.

Figure 1

Quizartinib therapy reduces marrow blast burden by the induction of either differentiation or cytotoxicity responses. (a, b) Comparison of blast burden and marrow cellularity at baseline and at best response time points. (c, d) Representative photomicrographs of two patients with differentiation and cytotoxic responses. (e) Graph of FLT3-ITD:WT allelic ratio, organized by color according to response. The ratio has been converted to ITD frequency (ITD/ITD+WT) for ease of graphical display.