Table 1.

Patient Characteristics.^*

Characteristic	All Patients (N = 26)	Patients with Virus-Positive Tumors (N = 17)	Patients with Virus- Negative Tumors (N = 9)
Age at enrollment — yr
Mean	70.5±8.1	67.5±6.0	76.3±8.6
Median (range)	68 (57 to 91)	67 (57 to 83)	76 (64 to 91)
Sex — no. (%)
Female	10 (38)	4 (24)	6 (67)
Male	16 (62)	13 (76)	3 (33)
Disease stage at study entry — no. (%)
IIIB	2 (8)	2 (12)	0
IV	24 (92)	15 (88)	9 (100)
Previous duration of disease — wk†
Mean	58.8±56.8	71.3±63.5	35.2±32.6
Median (range)	39 (3 to 227)	53 (3 to 227)	27 (5 to 104)
Baseline extent of disease — mm‡
Mean	81.7±53.9	88.7±63.1	68.6±28.7
Median (range)	69 (13 to 182)	62 (13 to 182)	75 (36 to 123)

^*Plus–minus values are means ±SD.

^†Previous duration of disease was measured from the date of diagnosis to the date of the first dose of study treatment. An unknown day of diagnosis was imputed as mid-month for one patient.

^‡The extent of disease was measured before treatment initiation as the sum of the longest diameters of tumor target lesions.