Table 2.
Final Diagnosis | |||||
---|---|---|---|---|---|
Luminal Findings | ICAD (N=38) | MMD (N=30) | V (N=8) | P-value (ICAD vs. MMD)* | |
Occlusion | ACA | 0 (0.0) | 2 (6.7) | 0 (0.0) | 0.95† |
MCA | 11 (28.9) | 6 (20.0) | 1 (12.5) | ||
ICA | 14 (36.8) | 12 (40.0) | 2 (25.0) | ||
SCA | 1 (2.6) | 0 (0.0) | 0 (0.0) | ||
None | 13 (34.2) | 10 (33.3) | 5 (62.5) | ||
Collaterals | None | 19 (50.0) | 6 (20.0) | 8 (100.0) | 0.033 |
Some | 15 (39.5) | 13 (43.3) | 0 (0.0) | ||
Pronounced | 4 (10.5) | 11 (36.7) | 0 (0.0) | ||
VMI Findings | |||||
Eccentric lesion | 24 (63.2) | 3 (10.0) | 0 (0.0) | 0.010 | |
Remodeling | Outward | 22 (57.9) | 2 (6.7) | 0 (0.0) | 0.003 |
T2 signal of VW | Heterogenous | 21 (55.3) | 0 (0.0) | 3 (37.5) | 0.006 |
Juxtaluminal hyperintensity | 20 (52.6) | 0 (0.0) | 0 (0.0) | ||
VW enhancement | Yes | 25 (65.8) | 4 (13.3) | 8 (100.0) | 0.010 |
Enhancement intensity | Mild | 16 (64.0) | 4 (100.0) | 0 (0.0) | 0.30 |
(if enhanced) | Moderate | 9 (36.0) | 0 (0.0) | 8 (100.0) | |
Pattern of enhancement | Focal | 2 (8.0) | 0 (0.0) | 0 (0.0) | 0.41 |
(if enhanced) | Homogeneous | 11 (44.0) | 4 (100.0) | 6 (75.0) | |
Heterogeneous | 12 (48.0) | 0 (0.0) | 2 (25.0) |
Values are no. (%) unless otherwise specified;
ACA = anterior cerebral artery; ICA = internal carotid artery; ICAD = intracranial atherosclerotic disease; LI = luminal imaging; MCA = middle cerebral artery; MMD = moyamoya disease; SCA = superior cerebellar artery; V = vasculitis; IVWM = vessel wall imaging;
Permutation-test based on the standard Chi-squared test statistic or trend statistic (collateral grade only); only ICAD and MMD groups were compared because the vasculitis group had only three patients;
Comparison of any occlusion vs. no occlusion.