Table 3.

Overall seizure risk by clinical characteristic

	Univariate		Adjusteda
Characteristic	OR; 95%CIb	p value	OR; 95%CIb	p value
Baseline
Agec	1.02;0.99–1.05	0.09	1.02;0.98–1.05	0.27
Female	1.29;0.62–2.66	0.48	1.35;0.63–2.89	0.44
Aneurysmal SAH etiology	1.92;0.57–6.52	0.30	1.79;0.51–6.04	0.36
Aneurysm location, anterior vs. posterior circ.	1.15;0.93–1.42	0.19	1.16;0.93–1.44	0.18
Severe Hunt-Hess scored	2.24;1.54–3.24	0.01	2.78;1.27–6.09	0.01
Severe SAH burdene	4.41;1.03–18.9	0.04	2.79;0.63–12.4	0.18
Intraparenchymal hemorrhage	1.62;0.74–3.57	0.22	0.81;0.33–2.01	0.64
Intraventricular hemorrhage	2.40;1.15–5.03	0.02	3.27;1.40–7.67	0.01
Acute Hydrocephalus	1.67;0.79–3.49	0.17	1.33;0.61–2.94	0.48
Treatment period, no prophylactic AEDsf	0.86;0.43–1.75	0.68	0.95; 0.42–2.11	0.89
Aneurysm treatment
Aneursym clipping	1.15;0.52–2.57	0.73	1.20;0.51–2.81	0.68
Seizure prophylaxis
AED administration	0.70;0.33–1.46	0.34	0.58;0.25–1.32	0.25
AED duration	1.01;0.93–1.10	0.85	1.02;0.93–1.13	0.56

^aAdjustment for neurologic grade on admission, cisternal SAH burden, and intraventricular hemorrhage;

^bSignificant predictors (p≤0.05) are reported as odds ratio & 95% confidence intervals;

^cWilcoxon-Mann-Whitney test;

^dAdmission Hunt-Hess score >3;

^e>1mm hemorrhage in all basal cisterns on contiguous CT slices;

^fTreatment period before versus after protocol change to no prophylactic AEDs.