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. Author manuscript; available in PMC: 2016 Jul 7.
Published in final edited form as: Cell Rep. 2016 Jun 16;16(1):48–55. doi: 10.1016/j.celrep.2016.05.073

Figure 2. 53BP1 Determines Break Order Independently of the DNA Damage Pathway.

Figure 2

(A and C) Igh alleles where location of the first break can be determined were divided into break-first-on-Sμ or -Sγ1 categories for the different mutants or treatments. Significance was calculated using Fisher’s exact test. Table S3 details the number of replicates and alleles analyzed. Plots represent the average frequency of each category across replicate experiments. N represents the amount of Igh alleles where break order could be determined across all replicates analyzed.

(B) Scheme shows the DSB repair pathway that is active during CSR.