Table 3.

Conditions that can provoke seizures.

Change in intracranial pathology	Infections in the immunocompromised	Chemotherapy/other treatments	Antibiotics	Medication side effects	Antiepileptic drug (AED) treatment failure
Progression of disease/recurrence of disease	Meningitis	Busulfan	Imipenem Cefepime	Metabolic/electrolyte derangements, particularly in sodium, magnesium, and calcium	Drug-drug interactions with antiepileptics
Intracranial process affecting the hypothalamic-pituitary axis or systemic tumor excretion of antidiuretic hormone	Encephalitis, particularly with HSV	Cyclosporine Ifosfamide	Penicillin Cephalosporins	Hepatic and/ or renal impairment accelerating toxic-metabolic disorders or decreasing drug clearance	Competition for protein binding changes serum antiepileptic drug levels
Surgical resection(s)	Intracranial abscess formation	Intrathecal cytarabine		Critical drug-drug interactions with AEDs
PRES		CAR T-cell therapy		Neurotoxicity
Radiation therapy induced edema or pseudoprogression		Combination of intrathecal liposomal cytarabine and high dose methotrexate		Elevation in blood pressure
Intracranial hemorrhage		L-asparaginase
Stroke, venous congestion stroke		Intrathecal methotrexate