Figure 2.

Scatter plot and fit of K₁ estimates (solid curve, blue) for ^99mTc-tetrofosmin using the model ${\mathit{K}}_1=\mathit{F}\left(1-\mathit{A}\mathbf{exp}\left(-\frac{\mathit{B}}{\mathit{F}}\right)\right)$ to the experimental data (filled circles, black) (R²=0.49) for the subgroup of 9 patients at rest and stress. The best fit curve gave the extraction parameters A=0.91±0.11; B=0.34±0.20 for ^99mTc-tetrofosmin. Insert: Comparison of the two models (1) ${\mathit{K}}_1=\mathit{F}\left(1-\mathit{A}\mathbf{exp}\left(-\frac{\mathit{B}}{\mathit{F}}\right)\right)$ (full line) and (2) ${\mathit{K}}_1=\mathit{F}\left(1-\mathbf{exp}\left(-\frac{\alpha \ast \mathit{F}+\beta }{\mathit{F}}\right)\right)$ (dotted line). In model (2) the capillary PS value is (α) * F + (β) = (0.091 ± 0.10) * F + (0.32 ± 0.16). ANOVA test revealed that there was no significant difference between the two models (p<0.001).