Table 1. Laboratory values at the time of scleroderma onset, at breast cancer diagnosis, at episcleritis onset, and at the time of the current presentation.

	Normal Range	Diffuse systemic sclerosis onset	Breast Cancer Diagnosis	Episcleritis onset	Current presentation	4 months after rituximab induction therapy
Time prior to current presentation (years)		-14	-10	-2	0	+0.3
White Blood Cell Count (×103/uL)	3.4-10.8	4.5	4.4	8.3	7.18	10.2
Hemoglobin (g/dL)	11.1-15.9	12.8	12.7	12.1	10.1	11.4
Hematocrit (%)	34.0-46.6	37.9	36.0	37.0	33.1	35.4
Mean cell volume (femtoliters)	80-100		89.2	90	91.9	83
Platelets (×103/uL)	155-379	246	210	293	356	290
Sodium (mMol/L)	134-144	139	141	139	138	140
Potassium (mMol/L)	3.5-5.2	4.1	4.2	4.3	4.0	4.1
BUN (mg/dL)	8-27	15	7	13	11	22
Creatinine (mg/dL)	0.57-1.00	0.6	0.6	0.55	0.50	.54
Glucose (mg/dL)	65-99	105	97	82	129	103
AST (iU/L)	0-40	25	29	28	23	18
ALT (iU/L)	0-32	19	21	27	22	10
Erythrocyte sedimentation rate (mm/hr)	0-40	25	29	28	23	9
C-Reactive protein (mg/L)	0-4.9	4	<1	2.7	14	2.5
ANA	Negative	1:160 homogeneous			1:160 homogeneous
Scl-70	Negative	Negative	Negative	Negative	Negative
Centromere	Negative	Negative			Negative
RNA polymerase III (units)	<20	Not done			33.4
THTO	Negative	Not Done			Negative
U3RNP	Negative	Not Done			Negative
U1RNP	Negative	Not Done			Negative
Anti-Smith	Negative	Not Done			Negative
Anti-dsDNA	Negative	Not Done			Negative
p-ANCA	Negative	Not Done		<1:20	<1:20
c-ANCA	Negative	Not Done		1:80	1:640
Anti-proteinase-3 (U/mL)	0-3.5	Not Done		47.5	39.9
Anti-myeloperoxidase (MPO)	<9.0	Not Done		<9.0	<9.0
Rheumatoid Factor (IU/mL)	0-13.5	Not Done		17.3
Cyclic Citrullinated peptide (units)	0-19	Not Done		3
Quantiferon gold	Negative	Not Done			Negative
Ca27-29 (U/mL)	0-37		40		39.8	46.8