Table 2.
Group I | Group II | Group IIIa | Group IIIb | p | ||
---|---|---|---|---|---|---|
C1 | C2 | |||||
End of treatment | 107 (106–107) | 107 (107–107) | 103 (102–104) | 101 (101–102) | 104 (103–105) | <0.001* |
Sig. with | C2*** | C2***,II*** | C1***, IIIa*** | |||
1 month post treatment | – | – | 102 (101–103) | 101 (101–102) | 106 (105–106) | 0.002* |
Sig. with | II** | II***, IIIa*** |
Data were described using median, minimum and maximum
C1 control infected non treated group corresponding to group IIIb, C2 control infected non treated group corresponding to group II and group IIIa; Group II: infected treated mice with miltefosine for 20 days; Group IIIa: infected treated mice with azithromycin for 20 days; Group IIIb: infected treated mice with combination of miltefosine and azithromycin for 10 days. * Significant at P < 0.05; ** significant at P < 0.01; *** significant at P < 0.001