Table 1.
Subgroups | Number of animals (n) | Microvascular leakage (NGL) | Leukocyte adhesion (number of leukocyte/100 μm of venular length/30 s) | Capillary perfusion (PCL) % reduction (compared to baseline) | Capillary red blood cell velocity (VRBC mm/s) |
---|---|---|---|---|---|
Sham-saline | 5 | 0.03 ± 0.01 | 0.5 ± 0.3 | 0 ± 4 | 0.20 ± 0.02 |
Hypo | 5 | 0.46 ± 0.04§° | 10 ± 2§° | 48 ± 4§° | 0.12 ± 0.03§° |
Hypo-M1 | 5 | 0.32 ± 0.03§°* | 6 ± 1§°* | 35 ± 3§°* | 0.17 ± 0.01§°* |
Hypo-M2 | 5 | 0.10 ± 0.02§°* | 2 ± 1* | 28 ± 4§°* | 0.19 ± 0.02* |
Hypo-L/M2 | 5 | 0.13 ± 0.03§°*+ | 3.0 ± 1.5* | 30 ± 2§°*+ | 0.24 ± 0.02* |
For capillary perfusion, data at the end of reperfusion were compared with those prior to hypoperfusion. Leukocyte adhesion: n = 45 venules for each entry. Data are reported as Mean ± SEM; §p < 0.01 vs. Baseline; °p < 0.01 vs. Sham-saline subgroup, *p < 0.01 vs. Hypo subgroup, +p < 0.01 vs. Hypo-M2 subgroup.