Table 3.
Maximum likelihood estimates for quadratic models when the different patient-level factors were investigated
| Skeletal muscle index | Gender (female vs. male) | Age, years (>65 vs. <65) | NLR (HNLR vs. LNLR) | ASA (III + IV vs. I + II) | Surgical approach (laparoscopic vs. open) | Tumor site (rectum vs. colon) | UICC stage (III + IV vs. I + II) | |||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Best-fit model | Two-stage formation | Polynomial | Two-stage formation | Two-stage formation | Two-stage formation | Two-stage formation | Two-stage formation | |||||||
| Fixed part | Estimate | SE | Estimate | SE | Estimate | SE | Estimate | SE | Estimate | SE | Estimate | SE | Estimate | SE |
| b 1 (constant) | 47.69 | (0.38)* | 50.15 | (0.99)* | 45.68 | (0.58)* | 49.48 | (1.65)* | 44.54 | (0.62)* | 42.17 | (0.95)* | 44.21 | (1.10)* |
| b (variable of interest) | −7.95 | (0.58)* | −3.79 | (0.11)* | −2.28 | (0.79)* | −2.68 | (0.62)* | −0.32 | (0.77) | 1.67 | (0.09) | 0.09 | (0.73) |
| b 2 (time linear) | 0.30 | (0.11)* | 0.33 | (0.11)* | 0.30 | (0.13)* | 0.05 | (0.19) | 0.21 | (0.15) | 0.52 | (0.16)* | 0.64 | (0.17)* |
| b 3 (time quadratic) | −0.03 | (0.01)* | −0.03 | (0.01)* | −0.03 | (0.01)* | −0.01 | (0.02) | −0.02 | (0.01)* | −0.03 | (0.01)* | −0.03 | (0.15)* |
| c (variable*time) | 0.13 | (0.09) | 0.15 | (0.10) | 0.08 | (0.08) | 0.15 | (0.06)a | −0.13 | (0.05)* | −0.20 | (0.09)* | ||
| Random part | ||||||||||||||
| Bp | 7.51 | (0.22) | 8.27 | (0.09) | 8.82 | (0.29) | 8.17 | (0.29) | 8.79 | (0.27) | 8.44 | (0.24) | 8.77 | (0.27) |
| 0.26 | (0.10) | 0.27 | (0.10) | 0.31 | (0.09) | 0.19 | (0.16) | 0.29 | (0.09) | 0.26 | (0.09) | 0.29 | (0.09) | |
| 0.24 | (0.23) | 0.01 | (0.18) | 0.05 | (0.17) | 0.07 | (0.29) | 0.09 | (0.18) | 0.11 | (0.19) | 0.05 | (0.16) | |
| Residual | 3.17 | (0.08) | 3.17 | (0.07) | 2.93 | (0.08) | 3.14 | (0.09) | 3.07 | (0.08) | 8.44 | (0.24) | 3.08 | (0.08) |
| Log likelihood | −5983.02 | −6045.44 | −4123.82 | −4332.86 | −5055.37 | −6064.41 | −5148.82 | |||||||
| AIC | 11,984.02 | 12,106.88 | 8265.64 | 8683.71 | 10,118.38 | 12,146.82 | 10,315.64 | |||||||
| BIC | 12,034.09 | 12,151.38 | 8312.36 | 8730.95 | 10,166.87 | 12,196.89 | 10,364.31 | |||||||
| Heteroscedasticity | Absent | Absent | Absent | Absent | Absent | Absent | Absent | |||||||
NLR neutrophil to lymphocyte ratio, ASA American Society of Anesthesiologists, UICC Union for International Cancer Control, HNLR high NLR, LNLR low NLR, SE standard error, AIC Akaike Information Criterion, BIC Bayesian Information Criterion
* p < 0.05