Table 4.

Multivariate quadratic growth with random intercept and random slope for patients LSMI

Skeletal muscle index	Estimate	(SE)	p value
Fixed part
Gender
Female versus male	−8.82	(0.88)	<0.01
Age (years)
>65 versus <65	−3.52	(0.88)	<0.01
NLR
HNLR versus LNLR	−1.89	(0.85)	0.03
ASA
III + IV versus I + II	−3.53	1.16	<0.01
Surgical approach
Laparoscopic versus Open	−0.68	1.20	0.60
Tumor site
Rectum versus colon	−0.91	0.89	0.31
UICC stage
III + IV versus I + II	0.27	0.86	0.75
Time*Laparoscopy	0.17	0.06	0.03
Time*Rectum	−0.13	0.11	0.25
Time*Stage III + IV	−0.19	0.09	0.04
Time linear	0.75	0.30	0.01
Time quadratic	−0.03	0.01	0.02
Random part
Bp	7.41	0.32
${\text{t}}_{\text{ij}}^{\text{p}}$	0.29	0.11
${\mathit{\xi }}_{\text{ij}}\left(\text{constant}\right)$	0.13	0.21
Residual	2.45	0.07
Log likelihood	−3038.85
AIC	6111.71
BIC	6195.49

NLR neutrophil to lymphocyte ratio, ASA American Society of Anesthesiologists, UICC Union for International Cancer Control, HNLR high NLR, LNLR low NLR, SE standard error, AIC Akaike Information Criterion, BIC Bayesian Information Criterion

Bolded p values indicate statistical significance at p < 0.05