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. 2016 Apr 21;47(3):697–702. doi: 10.1016/j.bjm.2016.04.014

Table 5.

Effect of the minimum inhibitory concentration (MIC)a of ozonized oil on enzymes activity of selected dermatophyte fungi.

M. gypseum M. canis T. interdigitale T. mentagrophytes T. rubrum
Keratinase Control 8.21 ± 3.86 26.32 ± 3.86 9.14 ± 2.06 18.98 ± 4.50 22.00 ± 4.70
Ozonized oilb 1.05 ± 0.98 6.11 ± 3.33 4.43 ± 3.04 6.17 ± 2.70 11.08 ± 5.74
% reduction 87.21 76.79 51.53 67.49 49.64



Urease Control 1.74 ± 0.12 0.97 ± 0.07 0.56 ± 0.04 0.48 ± 0.09 0.88 ± 0.15
Ozonized oil 0.82 ± 0.37 0.204 ± 0.05 0.16 ± 0.03 0.16 ± 0.07 0.20 ± 0.33
% reduction 52.87 78.97 71.43 66.67 77.27



Alkaline phosphatase Control 28.12 ± 3.00 35.92 ± 4.30 254.00 ± 12.98 229.43 ± 8.60 89.98 ± 11.0
Ozonized oil 1.66 ± 0.52 3.83 ± 5.38 16.52 ± 7.71 18.98 ± 14.87 9.93 ± 5.09
% reduction 94.10 89.34 93.50 91.73 88.96



Amylase Control 59.11 ± 2.22 22.07 ± 3.31 11.01 ± 2.52 8.58 ± 2.49 7.77 ± 2.01
Ozonized oil 21.11 ± 1.21 3.61 ± 1.81 4.82 ± 1.49 3.59 ± 1.30 2.82 ± 1.13
% reduction 64.29 83.64 56.22 58.16 63.71



Lipase Control 4.41 ± 0.96 5.71 ± 0.88 8.52 ± 1.31 9.41 ± 1.09 13.53 ± 1.40
Ozonized oil 1.81 ± 1.11 2.75 ± 0.99 3.71 ± 1.33 4.11 ± 1.87 6.65 ± 2.83
% reduction 58.96 51.84 56.46 56.32 50.85
a

MIC applied is that measured for growth.

b

Oil was dissolved in DEMSO.