Fig. 6.

Effects of BGOS supplementation on the 5-HT2AR and 5-HT1AR in the frontal cortex, 28 h after LPS or saline injections. (A) Representative western blot images of 5-HT2ARs in each group (top panel), and receptor:β-actin ratios, following densitometry of western blot images (bottom panel). There was a significant diet × treatment interaction, and cortical 5-HT2AR levels in Water/LPS mice were significantly greater than in BGOS/LPS and Water/Sal animals. Bars indicate significant group differences after post hoc (Bonferroni) analysis. (B) Western blot images and 5-HT1AR:β-actin ratios in the frontal cortex. There were neither a diet × treatment interaction nor main effects of BGOS or LPS on 5-HT1AR concentrations. Data are presented as mean ± SEM. ^∗p < 0.05. n = 12 mice/group for Water/SAL (WS in top panel) and BGOS/SAL (BS); n = 11 mice/group for Water/LPS (WL) and BGOS/LPS (BL).