Table 2.
Significant gray matter volume (GMV) alterations in pediatric obsessive-compulsive disorder patients vs. healthy controls.
| Brain region | Location | Cluster size (voxels) | t-value | Primary peak MNI coordinate (mm) | ||
|---|---|---|---|---|---|---|
| Pediatric | ||||||
| OCD > HCs | ||||||
| OFC | Left | 76 | 5.47 | −12.0 | 66 | −9 |
| Putamen | Left | 62 | 5.21 | −27.0 | 12 | 0 |
| Putamen | Right | 54 | 5.21 | 31.5 | 3 | 45 |
| Pediatric | ||||||
| OCD < HCs | ||||||
| IPL | Left | 69 | −5.77 | −62.0 | −51 | 39 |
p(FWE-corrected) < 0.05 with a minimum cluster size of 50 voxels; Abbreviations: FWE, family-wise error; GMV, gray matter volume; OCD, obsessive-compulsive disorder; HCs, healthy controls, OFC, orbitofrontal cortex; IPL, inferior parietal lobule; MNI, montreal neurological institute.