Table 2.
Sensitivity, Specificity, Positive Predictive Value (PPV), and Negative Predictive Value (NPV), with 95% confidence intervals (CI), for different Quick Mild Cognitive Impairment (Qmci) screen and Montreal Cognitive Assessment (MoCA) cut-off scores for cognitive impairment (mild cognitive impairment and dementia), without adjustment for age or education, compared with normal controls
| Cognitive | Sensitivity | Specificity | PPV | NPV | False | False |
| Screen | (95% CI) | (95% CI) | (95% CI) | (95% CI) | Positive | Negative |
| Cut-off score | (95% CI) | (95% CI) | ||||
| Prevalence of cognitive | ||||||
| impairment of 79% | ||||||
| Q mci | ||||||
| <65 | 94% | 80% | 94% | 80% | 6% | 20% |
| (91–96) | (71–87) | (91–96) | (71–87) | (4–7) | (13–29) | |
| <64 | 93% | 82% | 95% | 76% | 5% | 24% |
| (89–95) | (73–89) | (92–97) | (69–84) | (3–8) | (16–33) | |
| <63 | 91% | 85% | 96% | 74% | 4% | 26% |
| (88–94) | (76–91) | (93–97) | (64–81) | (3–7) | (19–36) | |
| <62† | 90% | 87% | 96% | 70% | 4% | 30% |
| (86–93) | (79–93) | (93–98) | (61–78) | (2–7) | (22–39) | |
| <61 | 88% | 92% | 98% | 69% | 2% | 31% |
| (84–91) | (85–96) | (95–99) | (60–76) | (1–5) | (24–40) | |
| <60 | 87% | 93% | 98% | 67% | 2% | 33% |
| (83–90) | (86–97) | (95–99) | (59–75) | (1–5) | (25–41) | |
| <59 | 85% | 96% | 99% | 65% | 1% | 35% |
| (81–89) | (90–99) | (96–100) | (56–72) | (0–4) | (28–44) | |
| <58 | 84% | 98% | 99% | 64% | 1% | 36% |
| (80–88) | (92–100) | (97–100) | (56–71) | (0–3) | (29–44) | |
| <57 | 84% | 100% | 100% | 64% | 0% | 36% |
| (79–87) | (95–100) | (98–100) | (55–71) | (0–2) | (29–45) | |
| <56 | 82% | 100% | 100% | 61% | 0% | 39% |
| (78–86) | (95–100) | (98–100) | (53–69) | (0–2) | (31–47) | |
| <55 | 81% | 100% | 100% | 59% | 0% | 41% |
| (76–85) | (95–100) | (98–100) | (52–67) | (0–2) | (33–48) | |
| MoCA | ||||||
| <26* | 96% | 58% | 89% | 80% | 11% | 20% |
| (93–98) | (48–68) | (85–92) | (68–88) | (8–15) | (12–32) | |
| <24** | 89% | 83% | 95% | 69% | 5% | 31% |
| (86–92) | (74–90) | (92–97) | (60–77) | (3–8) | (23–40) | |
| <23*** | 85% | 86% | 96% | 62% | 4% | 38% |
| (81–88) | (77–92) | (93–97) | (53–70) | (3–7) | (30–47) | |
| <22**** | 78% | 91% | 97% | 54% | 3% | 46% |
| (74–82) | (83–96) | (94–98) | (46–62) | (2–6) | (38–54) | |
†Cut-off for cognitive impairment selected from O’Caoimh et al. [42]. *Cut-off for cognitive impairment selected from Nasreddine et al. [9]. **Cut-off for cognitive impairment selected from Damian et al. [24]. ***Cut-off for cognitive impairment selected from Luis et al. [12]. ****Cut-off for mild cognitive impairment selected from Freitas et al. [26].