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. 2016 Mar 15;51(2):619–629. doi: 10.3233/JAD-150881

Table 3.

Sensitivity, specificity, positive predictive value (PPV), negative predictive value (NPV), and false positive and negative values for the Quick Mild Cognitive Impairment (Qmci) screen and Montreal Cognitive Assessment (MoCA), based upon cut-off scores for cognitive impairment (MCI and dementia), according to age and education (CI = 95% Confidence Interval)

Cognitive Age Edu Median N = X Cut-off Sensitivity Specificity PPV NPV False False
Screen Score score (95% CI) (95% CI) (95% CI) (95% CI) Positive Negative
(IQR) (95% CI) (95% CI)
Cognitive
Impairment
Controls
Qmci >75 <12 42 (50-26 = 24) 146/170 (86%) 97% 75% 96% 78% 4% 22%
70 (75-63 = 12) (92–99) (53–89) (91–98) (56–92) (2–7) (8–44)
>75 ≥12 47 (58-37 = 21) 59/76 (78%) <62 80% 94% 98% 55% 2% 49%
78 (81-71 = 10) (68–89) (69–100) (89–100) (36–73) (0–11) (27–64)
≤75 ≥12 47 (62-33 = 29) 73/110 (66%) 74% 95% 97% 64% 3% 36%
79 (84-75 = 9) (63–83) (80–99) (87–99) (50–76) (1–13) (24–50)
≤75 <12 41 (48-22 = 26) 77/97 (79%) 99% 85% 96% 94% 4% 6%
74.5 (82-65 = 17) (92–100) (61–96) (89–99) (71–100) (1–11) (0–29)
MoCA >75 <12 14.5 (19-10 = 9) 146/170 (86%) 99% 37.5% 91% 82% 9% 18%
25 (26-23 = 3) (95–100) (20–59) (85–94) (48–97) (6–15) (3–52)
>75 ≥12 19 (22-13 = 9) 59/76 (78%) <26 91.5% 71% 91.5% 71% 8% 29%
27 (29-25 = 4) (81–97) (44–89) (81–97) (44–89) (3–19) (11–56)
≤75 ≥12 18 (23-12 = 11) 73/110 (66%) 90% 73% 87% 79% 13% 21%
27 (30-25 = 6) (81–96) (56–86) (77–93) (62–91) (7–23) (9–38)
≤75 <12 16 (20-7 = 13) 77/97 (79%) 99% 50% 88% 91% 12% 9%
25.5 (27-24 = 3) (92–100) (28–72) (79–94) (57–100) (6–21) (1–43)