Table 2.
Between groups differences in verbal memory paradigm, FA and brain activation
| PD | HC | Statistic U/ta | p | ||
| Verbal memory paradigm | |||||
| HITS | 9.11 (4.14) | 12.29 (1.77) | 118 | 0.004 * | |
| CR | 11.66 (2.96) | 11.93 (2.20) | 238 | 0.874 | |
| FN | 5.77 (4.12) | 2.71 (1.77) | 123 | 0.006 * | |
| FP | 3.26 (2.94) | 3.07 (2.20) | 236 | 0.839 | |
| Fractional Anisotropy | |||||
| UF | L | 0.059 (0.003) | 0.059 (0.003) | –0.203a | 0.840 |
| R | 0.059 (0.003) | 0.060 (0.003) | –0.903a | 0.371 | |
| PCT | L | 0.044 (0.003) | 0.041 (0.003) | 3.046a | 0.004 * |
| R | 0.055 (0.003) | 0.054 (0.003) | 1.379a | 0.174 | |
| ACT | L | 0.055 (0.002) | 0.057 (0.003) | 173 | 0.035 |
| R | 0.039 (0.002) | 0.041 (0.002) | –3.314a | 0.002 * | |
| Learning Brain Activation | |||||
| MTL | L | 0.107 (0.194) | 0.058 (0.224) | 0.779a | 0.440 |
| R | –0.222 (0.293) | –0.060 (0.230) | 155 | 0.017 | |
| IOFC | L | 0.075 (0.312) | 0.260 (0.336) | –1.880a | 0.066 |
| R | 0.003 (0.340) | 0.265 (0.306) | –2.583a | 0.013 * | |
| Recognition Brain Activation | |||||
| MTL | L | 0.283 (0.595) | 0.124 (0.230) | 188 | 0.257 |
| R | 0.061 (0.600) | 0.007 (0.252) | 201 | 0.401 | |
| IOFC | L | –0.047 (1.71) | 0.392 (0.473) | 175 | 0.153 |
| R | 0.437 (1.71) | 0.431 (0.340) | 138 | 0.023 |
Values are expressed as the mean (SD) unless otherwise noted. *Significant corrected for multiple comparisons by Bonferroni’s procedure. PD = Parkinson’s disease; HC = Healthy controls; SD = Standard Deviation; CR = Correct Rejections; FN = False Negatives; FP = False Positives; L = Left; R = Right; UF = Uncinate Fasciculus; PCT = Posterior Cingulate Tract; ACT = Anterior Cingulate Tract; MTL = Medial Temporal Lobe; IOFC = Inferior Orbitofrontal Cortex.