Table 1.
Progression rate at 4.5 years (ITT recurrence population)
| 1 year | 3 years | 4.5 years | ||||
| HAL (n = 255) | WL (n = 261) | HAL (n = 255) | WL (n = 261) | HAL (n = 255) | WL (n = 261) | |
| Number (%) of patients with progression | 15 (5.9) ± | 23 (8.8) | 26 (10.2) † | 38 (14.6) | 31 (12.2) * | 46 (17.6) |
| Ta to CIS | 2 (0.8) | 5 (1.6) | 2 (0.8) | 10 (3.8) | 4 (1.6) | 11 (4.2) |
| Ta to T1 | 4 (1.6) | 7 (2.7) | 9 (3.5) | 8 (3.0) | 10 (3.9) | 9 (3.4) |
| Ta to≥T2 | 2 (0.8) | 3 (1.2) | 4 (1.6) | 5 (1.9) | 4 (1.6) | 8 (3.1) |
| CIS to T1 | 2 (0.8) | 1 (0.4) | 3 (1.2) | 2 (0.8) | 3 (1.2) | 2 (0.8) |
| T1 to≥T2 | 3 (1.2) | 3 (1.1) | 3 (1.2) | 5 (1.9) | 3 (1.2) | 5 (1.9) |
| Grade 1 to Grade 3 | 0 | 2 (0.8) | 3 (1.2) | 5 (1.9) | 4 (1.6) | 7 (2.7) |
| Death due to bladder cancer | 2 (0.8) | 2 (0.8) | 2 (0.8) | 3 (1.1) | 3 (1.2) | 4 (1.5) |
± p-value = 0.239 (Fisher’s exact test). † p-value = 0.143 (Fisher’s exact test). * p-value = 0.085 (Fisher’s exact test).