Fig.1.

A). Platelet tPLA₂ activity at baseline in healthy elderly and MCI subjects, who showed a significantly higher value. B) Correlation between MMSE score and tPLA₂ activity in MCI patients at baseline. Note that when MMSE values are higher, enzymatic activity is lower. C) tPLA₂ activity of MCI patients at baseline falls into two groups on the bases of the MMSE score: subjects with MMSE score <26 (Subgroup 1) had enzymatic activity significantly higher than subjects with MMSE score ≥26 (Subgroup 2), whose values were comparable to those of healthy elderly (dotted line). D) Correlation between the MMSE score at baseline and tPLA₂ activity changes before and after the intervention (Δ), in the experimental group of MCI patients. Δ= tPLA₂ activity at FU- tPLA₂ activity at baseline. E) Effect of cognitive stimulation on tPLA₂ activity of MCI patients Subgroups 1 and 2. Only in Subgroup 1, the training induced a significant decrease.