Table 4.

Engagement-related increases in brain activity

Region	MNI Coordinates (x, y, z)			BA	Cluster Size	Net Effect Size	% Reliable Change	Group × Time (Pre-Post) Interaction p-value
High Challenge (Posttest >  Pretest)
L Mid Cingulate Gyrus	–6	–4	30	24	47	1.73	0.78	0.00
R Precuneus	20	–62	44	7	34	1.09	0.65	0.01
L Intraparietal Sulcus	–38	–59	51	40	29	0.84	0.26	0.01
R Inferior Temporal Gyrus	56	–64	–7	37	29	1.02	0.57	0.02
L Middle Temporal Gyrus	–55	–53	–4	21	98	0.91	0.65	0.02
L Postcentral (Ventral) Gyrus	–40	–32	51	2/40	168	0.81	0.52	0.10
R SupraMarginal Gyrus	56	–25	40	2/3/4	38	0.69	0.57	0.10
L Putamen	–26	–1	–5	–	47	0.73	0.65	0.11
L Precentral Gyrus	–27	–12	66	6	63	0.65	0.65	0.13
L Postcentral (Dorsal) Gyrus	–16	–34	69	3/4	43	0.60	0.61	0.17
L Thalamus	–4	–10	5	–	40	0.64	0.52	0.21
Low Challenge (Posttest >  Pretest)
R Precentral Gyrus	26	–17	73	6	41	0.65	0.43	0.18

Notes. Regions are sorted according to interaction significance. L = Left, R = Right, BA = Approximate Brodmann Area. Only increases in brain activity were significant using a whole brain threshold of p <  0.01, corrected. Post-hoc Group × Time interactions were considered significant at p <  0.05.