Table 1.
Transfection efficiency of the liposomes in cultured primary skin cells. The percentages of transfected cells were analyzed 4 h post-treatment with a final concentration of 25 nm small RNA molecules (⁎) or 24 h with 50 nm (†). Grey colored: transfection conditions as described in Ref. [1] and Fig. 4C.
| % transfected cells | siRNA⁎ | Pre-miR⁎ | Anti-miR⁎ | Anti-miR† |
|---|---|---|---|---|
| Psoriasis-induced KCs | ||||
| HiPerfect | 99.9 | 49.3 | 5.0 | |
| SEC | 99.9 | 41.7 | 40.8 | |
| DDC642 | 99.9 | 46.8 | 12.0 | |
| Normal KCs | ||||
| HiPerfect | 99.9 | 20.7 | 37.2 | 29.2 |
| SEC | 99.9 | 16.6 | 63.0 | 94.2 |
| DDC642 | 99.9 | 69.1 | 73.2 | 96.0 |
| Melanocytes | ||||
| HiPerfect | 99.9 | 30.9 | 8.14 | |
| SEC | 99.9 | 49.3 | 61.3 | |
| DDC642 | 99.9 | 46.6 | 25.5 |