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. 2016 Jun 16;2016:6586857. doi: 10.1155/2016/6586857

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Copyright © 2016 Yung-Ray Hsu et al.

This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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The concentrations of NO in the aqueous humor as measured by ELISA. The concentrations of NO in the aqueous humor of EIU rats (a) and in RAW 264.7 cells treated with LPS (b). The aqueous humor was isolated under control conditions (Ctrl), pretreatment with LPS (LPS), and pretreatment with low-dose bortezomib (VL) or high-dose bortezomib (VH). LPS injection increased the NO production in the aqueous humor of EIU rats, and treatment with bortezomib significantly decreased the NO concentration in the aqueous humor in a dose-dependent manner. The symbols “∗” and “#” indicate statistical significance.