Figure 8.

(a) Immunofluorescent staining for glucagon (green color), BrdU (red color), and DAPI (blue color) in human islet grafts from PSN632408- and vehicle-treated mice with normoglycaemia at 4 weeks after transplantation. White arrows show glucagon/BrdU copositive cells in human islet grafts. (b) Percentage of glucagon/BrdU copositive cells among total glucagon positive cells in human islet grafts. The average percent of glucagon/BrdU copositive cells among total glucagon positive cells was significantly higher in PSN632408-treated mice (n = 9) compared with vehicle-treated mice (n = 4) (^∗∗∗ P < 0.001).