Table 4.
Risk factors for GO development in juvenile GD patients: univariate logistic regression.
| Factor | Value | β | OR | 95% CI | P | |
|---|---|---|---|---|---|---|
| Gender | Female | 1.000 | ||||
| Male | 1.181 | 3.259 | 1.150 | 9.235 | 0.026 | |
|
| ||||||
| Smoking | No | 1.000 | ||||
| Yes | 2.061 | 7.857 | 2.285 | 27.017 | 0.001 | |
|
| ||||||
| Family history of thyroid disease | No | 1.000 | ||||
| Yes | 1.261 | 3.529 | 1.581 | 7.878 | 0.002 | |
|
| ||||||
| Drug-induced hypothyroidism | No | 1.000 | ||||
| Yes | 0.863 | 2.371 | 0.793 | 7.086 | 0.122 | |
|
| ||||||
| Stress before GD | No | 1.000 | ||||
| Yes | 1.377 | 3.963 | 1.651 | 9.516 | 0.002 | |
|
| ||||||
| FT4, pmol/L | 0–35.99 | 1.000 | ||||
| 36.00+ | 1.764 | 5.833 | 2.407 | 14.137 | <0.001 | |
|
| ||||||
| FT3, pmol/L | 0–11.99 | 1.000 | ||||
| 12.00+ | 1.535 | 4.643 | 1.901 | 11.338 | 0.001 | |
|
| ||||||
| TSH, mU/L | 0.020+ | 1.000 | ||||
| 0–0.019 | 0.520 | 1.683 | 0.765 | 3.700 | 0.195 | |
|
| ||||||
| AntiTPO, kU/L | 0–79 | 1.000 | ||||
| 80+ | 0.526 | 1.692 | 0.773 | 3.706 | 0.188 | |
|
| ||||||
| TRAb, U/L | 0–15.99 | 1.000 | ||||
| 16.00+ | 2.303 | 10.000 | 3.487 | 28.679 | <0.001 | |
|
| ||||||
| AntiTG, kU/L | 0–79 | 1.000 | ||||
| 80+ | −0.251 | 0.778 | 0.230 | 2.628 | 0.686 | |
|
| ||||||
| Age at the diagnosis, years | 0–17 | 1.000 | ||||
| 18+ | 0.087 | 1.091 | 0.512 | 2.324 | 0.822 | |
β: regression coefficient; OR: odds ratio; CI: confidence interval.