Table 1.
Potential vaccine candidates selected by the Vaxign program. Localization and length were obtained by the Vaxign program, antigenic score was obtained by the VaxiJen program, and the number of B-cell epitopes was obtained from both BCPreds and AAP methods. The calculated ratio between the number of B-epitopes and protein length is also shown. The two candidates eliminated because of a low antigenic score are shown in italics.
| Protein accession | Description | ID | Localization | Length (aa) | Vaxijen score | BCPreds B-epitopes | AAP B-epitopes | ||
|---|---|---|---|---|---|---|---|---|---|
| N | Ratio N/length | N | Ratio N/length | ||||||
| YP_001000996.1 | Flagellin B | FlaB | Extracellular | 576 | 0.7650 | 10 | 0.017 | 11 | 0.019 |
| YP_001000997.1 | Flagellin A | FlaA | Extracellular | 576 | 0.8185 | 11 | 0.019 | 12 | 0.021 |
|
| |||||||||
| YP_001001371.1 | Flagellar hook protein | FlgE | Extracellular | 838 | 0.7659 | 16 | 0.019 | 18 | 0.021 |
| YP_001000562.1 | Flagellin protein family | Extracellular | 750 | 0.6965 | 15 | 0.020 | 15 | 0.020 | |
| YP_001000248.1 | Flagellar capping protein | FliD | Extracellular | 642 | 0.7021 | 11 | 0.017 | 11 | 0.017 |
| YP_001000204.1 | Putative periplasmic protein | OMP | 553 | 0.6702 | 11 | 0.021 | 11 | 0.021 | |
| YP_001000654.1 | Putative periplasmic protein | OMP | 553 | 0.6702 | 11 | 0.021 | 11 | 0.021 | |
| YP_999769.1 | Flagellar hook protein | FlgE-1 | Extracellular | 545 | 0.6567 | 10 | 0.018 | 12 | 0.022 |
| YP_001001115.1 | Flagellar hook-associated protein | FlgK | Extracellular | 608 | 0.5836 | 11 | 0.018 | 10 | 0.016 |
| YP_001000153.1 | TonB-dependent receptor, putative, degenerate | OMP | 704 | 0.5437 | 12 | 0.017 | 9 | 0.013 | |
| YP_001000945.1 | N-Acetylmuramoyl-L-alanine amidase | OMP | 659 | 0.6475 | 9 | 0.014 | 11 | 0.017 | |
| YP_001001027.1 | Serine protease | OMP | 1121 | 0.5268 | 9 | 0.008 | 11 | 0.010 | |
| YP_001000437.1 | Putative OMP | OMP | 508 | 0.6122 | 9 | 0.018 | 6 | 0.012 | |
| YP_999838.1 | Hypothetical protein | OMP | 400 | 0.6809 | 5 | 0.013 | 9 | 0.023 | |
| YP_999817.1 | Hypothetical protein | OMP | 315 | 0.7827 | 6 | 0.019 | 7 | 0.022 | |
| YP_001000383.1 | Flagellar basal body L-ring protein | FlgH | OMP | 232 | 0.6978 | 6 | 0.026 | 4 | 0.017 |
| YP_001000935.1 | Major OMP | PorA | OMP | 424 | 0.6051 | 5 | 0.012 | 5 | 0.012 |
| YP_001001008.1 | Phospholipase A | PldA | OMP | 329 | 0.5819 | 4 | 0.012 | 3 | 0.009 |
| YP_001001257.1 | TonB-dependent heme receptor | ChuA | OMP | 702 | 0.6213 | 7 | 0.010 | 5 | 0.007 |
| YP_001000615.1 | Hypothetical protein | Extracellular | 294 | 0.5498 | 3 | 0.010 | 3 | 0.010 | |
| YP_001000663.1 | Surface-exposed lipoprotein | JlpA | OMP | 372 | 0.6642 | 2 | 0.005 | 3 | 0.008 |
| YP_001000261.1 | Hypothetical protein | OMP | 309 | 0.5149 | 2 | 0.006 | 3 | 0.010 | |
| YP_001000503.1 | Hypothetical protein | Extracellular | 444 | 0.4603 | / | / | / | / | |
| YP_001000297.1 | Major antigenic peptide | PEB4 | OMP | 273 | 0.4511 | / | / | / | / |