Table 2.
Potential vaccine candidates selected after blast analysis. tblastn analyses were performed for each amino acid sequence against both C. jejuni and C. coli whole genomes available on the NCBI site. The amount and percentage of sharing among the available genomes were determined. A blastp analysis was also performed against the host Gallus gallus. The six candidates eliminated because of poor sharing among Campylobacter strains are shown in italics.
| Protein accession | Description | ID | Sharing among C. jejuni strains | Sharing among C. coli strains |
Similarity in Gallus gallus | ||
|---|---|---|---|---|---|---|---|
| N/93 | % | N/9 | % | ||||
| YP_001000996.1 | Flagellin B | FlaB | 77 | 83 | 9 | 100 | No |
| YP_001000997.1 | Flagellin A | FlaA | 75 | 81 | 9 | 100 | No |
|
| |||||||
| YP_001001371.1 | Flagellar hook protein | FlgE | 15 | 16 | 8 | 89 | No |
| YP_001000562.1 | Flagellin protein family | 93 | 100 | 9 | 100 | No | |
| YP_001000248.1 | Flagellar capping protein | FliD | 38 | 41 | 9 | 100 | No |
| YP_001000204.1 | Putative periplasmic protein | 2 | 2 | 9 | 100 | No | |
| YP_001000654.1 | Putative periplasmic protein | 2 | 2 | 9 | 100 | No | |
| YP_999769.1 | Flagellar hook protein | FlgE-1 | 93 | 100 | 9 | 100 | No |
| YP_001001115.1 | Flagellar hook-associated protein | FlgK | 93 | 100 | 9 | 100 | No |
| YP_001000153.1 | TonB-dependent receptor, putative, degenerate | 90 | 97 | 9 | 100 | No | |
| YP_001000945.1 | N-Acetylmuramoyl-L-alanine amidase | 93 | 100 | 9 | 100 | No | |
| YP_001001027.1 | Serine protease | PEB4 | 6 | 6 | 1 | 11 | No |
| YP_001000437.1 | Putative OMP | 89 | 96 | 6 | 67 | No | |
| YP_999838.1 | Hypothetical protein | 93 | 100 | 9 | 100 | No | |
| YP_999817.1 | Hypothetical protein | 92 | 99 | 9 | 100 | No | |
| YP_001000383.1 | Flagellar basal body L-ring protein | FlgH | 93 | 100 | 9 | 100 | No |
| YP_001000935.1 | Major OMP | PorA | 81 | 87 | 9 | 100 | No |
| YP_001001008.1 | Phospholipase A | PldA | 92 | 99 | 9 | 100 | No |
| YP_001001257.1 | TonB-dependent heme receptor | ChuA | 93 | 100 | 9 | 100 | No |
| YP_001000615.1 | Hypothetical protein | 64 | 69 | 9 | 100 | No | |
| YP_001000663.1 | Surface-exposed lipoprotein | JlpA | 93 | 100 | 9 | 100 | No |
| YP_001000261.1 | Hypothetical protein | 92 | 99 | 9 | 100 | No | |