Skip to main content
NCBI home page
Journal of Neurology, Neurosurgery, and Psychiatry logoLink to Journal of Neurology, Neurosurgery, and Psychiatry
. 1977 Jul;40(7):695–698. doi: 10.1136/jnnp.40.7.695

Verbal learning dysfunction with combined centre median and amygdala lesions

M F Jurko 1, O J Andy 1
PMCID: PMC492805  PMID: 915514

Abstract

Stereotaxic lesions in either or both amygdala did not impair verbal learning ability (presented by ear as a paired-associates test). Centre median lesions alone did not impair this form of learning; however, when combined with a left amygdala lesion a significant decrease in scores occurred which persisted for up to two years after operation. The data support a hypothesis that medial thalamic structures have alerting functions in learning mechanisms.

Full text

PDF
695

Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. BARBIZET J. Defect of memorizing of hippocampal-mammillary origin: a review. J Neurol Neurosurg Psychiatry. 1963 Apr;26:127–135. doi: 10.1136/jnnp.26.2.127. [DOI] [PMC free article] [PubMed] [Google Scholar]
  2. Blakemore C. B., Falconer M. A. Long-term effects of anterior temporal lobectomy on certain cognitive functions. J Neurol Neurosurg Psychiatry. 1967 Aug;30(4):364–367. doi: 10.1136/jnnp.30.4.364. [DOI] [PMC free article] [PubMed] [Google Scholar]
  3. Drachman D. A., Arbit J. Memory and the hippocampal complex. II. Is memory a multiple process? Arch Neurol. 1966 Jul;15(1):52–61. doi: 10.1001/archneur.1966.00470130056005. [DOI] [PubMed] [Google Scholar]
  4. Fedio P., Van Buren J. M. Memory and perceptual deficits during electrical stimulation in the left and right thalamus and parietal subcortex. Brain Lang. 1975 Jan;2(1):78–100. doi: 10.1016/s0093-934x(75)80056-3. [DOI] [PubMed] [Google Scholar]
  5. Gol A., Faibish G. M. Effects of human hippocampal ablation. J Neurosurg. 1967 Apr;26(4):390–398. doi: 10.3171/jns.1967.26.4.0390. [DOI] [PubMed] [Google Scholar]
  6. Jurko M. F., Andy O. J. Psychological changes correlated with thalamotomy site. J Neurol Neurosurg Psychiatry. 1973 Oct;36(5):846–852. doi: 10.1136/jnnp.36.5.846. [DOI] [PMC free article] [PubMed] [Google Scholar]
  7. Krayenbühl H., Siegfried J., Kohenof M., Yasargil M. G. Is there a dominant thalamus? Confin Neurol. 1965;26(3):246–249. doi: 10.1159/000104033. [DOI] [PubMed] [Google Scholar]
  8. MCFIE J. Psychological effects of stereotaxic operations for the relief of parkinsonian symptoms. J Ment Sci. 1960 Oct;106:1512–1517. doi: 10.1192/bjp.106.445.1512. [DOI] [PubMed] [Google Scholar]
  9. Milner B. Disorders of learning and memory after temporal lobe lesions in man. Clin Neurosurg. 1972;19:421–446. doi: 10.1093/neurosurgery/19.cn_suppl_1.421. [DOI] [PubMed] [Google Scholar]
  10. Ojemann G. A., Hoyenga K. B., Ward A. A., Jr Prediction of short-term verbal memory disturbance after ventrolateral thalamotomy. J Neurosurg. 1971 Aug;35(2):203–210. doi: 10.3171/jns.1971.35.2.0203. [DOI] [PubMed] [Google Scholar]
  11. Ojemann G. A. Mental arithmetic during human thalamic stimulation. Neuropsychologia. 1974 Jan;12(1):1–10. doi: 10.1016/0028-3932(74)90021-9. [DOI] [PubMed] [Google Scholar]
  12. Ojemann G., Fedio P. Effect of stimulation of the human thalamus and parietal and temporal white matter on short-term memory. J Neurosurg. 1968 Jul;29(1):51–59. doi: 10.3171/jns.1968.29.1.0051. [DOI] [PubMed] [Google Scholar]
  13. SPIEGEL E. A., WYCIS H. T., ORCHINIK C. W., FREED H. The thalamus and temporal orientation. Science. 1955 May 27;121(3152):771–772. doi: 10.1126/science.121.3152.771. [DOI] [PubMed] [Google Scholar]
  14. VICTOR M., ANGEVINE J. B., Jr, MANCALL E. L., FISHER C. M. [Memory loss with lesions of hippocampal formation. Report of a case with some remarks on the anatomical basis of memory]. Arch Neurol. 1961 Sep;5:244–263. doi: 10.1001/archneur.1961.00450150010002. [DOI] [PubMed] [Google Scholar]
  15. WILLIAMS M., PENNYBACKER J. Memory disturbances in third ventricle tumours. J Neurol Neurosurg Psychiatry. 1954 May;17(2):115–123. doi: 10.1136/jnnp.17.2.115. [DOI] [PMC free article] [PubMed] [Google Scholar]

Articles from Journal of Neurology, Neurosurgery, and Psychiatry are provided here courtesy of BMJ Publishing Group

RESOURCES