Table 2. Growth Mediator and Androgen-Regulated mRNA Expression in the Prostate (PRO), Testis (TES), Mammary (MAM) and Ovary (OVA) Tissue of Adult Sgta-null Mice.
| Gene | Males |
Females |
||||||
|---|---|---|---|---|---|---|---|---|
| Tissue | WT | Sgta+/− | Sgta−/− | Tissue | WT | Sgta+/− | Sgta−/− | |
| Growth Mediators | ||||||||
| Ghr | PRO | 12.02 ± 0.98 | 10.21 ± 1.22 | 9.34 ± 1.32 | MAM | 4.44 ± 0.64 | 5.15 ± 0.57 | 4.93 ± 0.63 |
| Ghr | TES | 0.05 ± 0.004 | 0.05 ± 0.001 | 0.05 ± 0.002 | OVA | 2.42 ± 0.19a | 3.16 ± 0.20ab | 3.42 ± 0.33b |
| Igf-1 | PRO | 1.28 ± 0.11 | 1.16 ± 0.10 | 0.96 ± 0.09 | MAM | 3.84 ± 0.38ab | 5.21 ± 0.62a | 3.25 ± 0.60b |
| Igf-1 | TES | 0.28 ± 0.03 | 0.28 ± 0.02 | 0.28 ± 0.02 | OVA | 2.24 ± 0.17 | 2.54 ± 0.15 | 2.77 ± 0.16 |
| Igf-1r | PRO | 11.46 ± 0.81 | 11.67 ± 0.92 | 10.53 ± 0.86 | MAM | 4.22 ± 0.42 | 4.29 ± 0.19 | 4.63 ± 0.48 |
| Igf-1r | TES | 0.87 ± 0.07 | 0.77 ± 0.04 | 0.89 ± 0.05 | OVA | 3.56 ± 0.25 | 3.72 ± 0.22 | 3.68 ± 0.18 |
| Androgen-Regulated | ||||||||
| Hp-1 | PRO | 0.07 ± 0.03 | 0.05 ± 0.02 | 0.02 ± 0.02 | MAM | 2.56 ± 0.31 | 3.39 ± 0.32 | 3.48 ± 0.56 |
| Hp-1 | OVA | 0.39 ± 0.03 | 0.41 ± 0.03 | 0.42 ± 0.03 | ||||
| Odc1 | PRO | 0.35 ± 0.03 | 0.38 ± 0.03 | 0.34 ± 0.03 | MAM | 0.16 ± 0.01 | 0.17 ± 0.01 | 0.17 ± 0.01 |
| Odc1 | TES | 0.93 ± 0.05 | 0.90 ± 0.04 | 0.94 ± 0.06 | OVA | 0.39 ± 0.03 | 0.41 ± 0.03 | 0.42 ± 0.03 |
| Rhox5 | TES | 0.84 ± 0.05 | 0.77 ± 0.04 | 0.94 ± 0.09 | OVA | 0.89 ± 0.13 | 1.00 ± 0.15 | 1.04 ± 0.21 |
Means with different letters are significantly different, P < 0.05.