Table 1. Enrichment analysis of TFBSs in promoters of zebrafish/tilapia divergently expressed genes within the GO term “regulation of apoptotic process.”.
| TF | Zebrafish/tilapia divergently expressed orthologues |
Zebrafish/tilapia non divergently expressed orthologues |
Odds ratio | P value | ||
|---|---|---|---|---|---|---|
| Present | Absent | Present | Absent | |||
| STAT1 | 15 | 9 | 8 | 33 | 6.63 | 9.84E-04 |
| NFKB1 | 13 | 11 | 8 | 33 | 4.74 | 5.98E-03 |
| Bcl6 | 14 | 10 | 10 | 31 | 4.23 | 8.44E-03 |
| Esrrb | 10 | 14 | 6 | 35 | 4.06 | 1.95E-02 |
| CEBPA | 16 | 8 | 15 | 26 | 3.40 | 2.31E-02 |
| REL | 9 | 15 | 5 | 36 | 4.21 | 2.73E-02 |
| YY1 | 12 | 12 | 9 | 32 | 3.48 | 2.83E-02 |
| Stat5a::Stat5b | 12 | 12 | 9 | 32 | 3.48 | 2.83E-02 |
| Nkx3-2 | 10 | 14 | 7 | 34 | 3.40 | 4.16E-02 |
| ESRRA | 11 | 13 | 8 | 33 | 3.42 | 4.61E-02 |
The present or absence of a TFBS motif was identified by FIMO. Odds ratio quantifies the effect of the presence of a motif from this class on the odds that it would be divergently expressed. P values were calculated using Fisher’s exact test against the null hypothesis (a no-biased distribution of TFBS in the promoters of the genes of interest).