Table 2.

Alleles and genotypes of the ADAM10 SNPs in the cases and controls of cohorts I and II.

	Cohort I			Cohort II
	Cases n (%)	Controls n (%)	p Values	Cases n (%)	Controls n (%)	p Values
rs653765 G > A
G/A	560 (83.6)/110 (16.4)	538 (82.8)/112 (17.2)	0.816	272 (84.5)/50 (15.5)	336 (82.8)/70 (17.2)	0.582
GG/GA/AA	233 (69.6)/94 (28.1)/8 (2.4)	223 (68.6)/92 (28.3)/10 (3.1)	0.922	115 (71.4)/42 (26.1)/4 (2.5)	140 (69.0)/56 (27.6)/7 (3.4)	0.584
GG/GA + AA	233 (69.6)/102 (30.5)	229 (68.6)/102 (31.4)	0.815	115 (71.4)/46 (28.6)	140 (69.0)/63 (31.0)	0.666
GG + GA/AA	327 (97.6)/8 (2.4)	315 (96.9)/10 (3.1)	0.635	157 (97.5)/4 (2.5)	196 (96.6)/7 (3.4)	0.592
rs514049 A > C
A/C	640 (95.5)/30 (4.5)	600 (92.3)/50 (7.7)	0.020	309 (96.0)/13 (4.0)	368 (90.6)/38 (9.4)	0.008
AA/AC/CC	309 (92.2)/22 (6.6)/4 (1.2)	278 (85.5)/44 (13.5)/3 (0.9)	0.100	150 (93.2)/9 (5.6)/2 (1.2)	170 (83.7)/28 (13.9)/5 (2.5)	0.017
AA/AC + CC	309 (92.2)/26 (7.8)	278 (85.5)/47 (14.56)	0.009	150 (93.2)/11 (6.8)	170 (83.7)/33 (16.3)	0.009
AA + AC/CC	331 (98.8)/4 (1.2)	322 (99.1)/3 (0.9)	0.691	159 (98.8)/2 (1.2)	198 (97.5)/5 (2.5)	0.398

p Values have been adjusted for gender and age.