Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2016 Jun 30;6:28916. doi: 10.1038/srep28916

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

Copyright © 2016, Macmillan Publishers Limited

This work is licensed under a Creative Commons Attribution 4.0 International License. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in the credit line; if the material is not included under the Creative Commons license, users will need to obtain permission from the license holder to reproduce the material. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/

PMC Copyright notice

Whole-cell voltage-clamp recordings (V_hold = −65.5 mV) were made on DACs in flat-mount retinas isolated from cone-function-only mice. (a) A typical DAC exhibited a light-evoked inward current immediately after light onset (ON response). (b) In contrast to the cell in (a), this cell had an additional light-evoked inward current at light offset (OFF response, indicated by an arrow). (c) A typical cell displayed an inward current at ~1 s after light onset (d-ON response, arrow) between the ON and OFF responses. Stimulation bar under each trace shows timing of a 470-nm light pulse. Light stimulus duration was 3 s for (a) and (c) and 2 s for (b). (d) Of a total of 86 cells tested, 68.6% only had ON responses (black bar), 20.9% exhibited ON and OFF responses (grey bar), and 10.5% had all three classes of light responses (striped bar).