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. 2016 Jun 30;6:28916. doi: 10.1038/srep28916

Figure 2. L-AP4 blocks ON responses of DACs that have an excitatory reversal potential.

Figure 2

(a) The ON response of a DAC (top trace) was completely blocked by L-AP4 (bottom trace). (b) This cell had ON and OFF responses (top trace). The bottom trace shows that the ON response was blocked by L-AP4 (indicated by an arrow), whereas the OFF response was still persistent (indicated by an arrowhead). Stimulation bar under each trace shows timing of a 470-nm light pulse. Light stimulus duration was 2 s for (a) and 3 s for (b). (c) Normalized current-voltage relation of the peak ON responses. Data points represent the average normalized value of the peak current amplitude at each holding potential. The curve indicates that the reversal potential of the ON response was 2.5 mV.