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. 2016 Jun 30;6:28916. doi: 10.1038/srep28916

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Excitatory ON responses are mediated by ON bipolar cells directly (red) and indirectly via ipRGCs (violet). OFF inhibition is mediated by type 2 and 3a OFF bipolar cells through GABAergic/glycinergic amacrine cells (cyan), whereas ON inhibition (d-ON response) is mediated by type 1 OFF bipolar cells via glycinergic amacrine cells (orange). GC: ganglion cell; ONL: outer nuclear layer; OPL: outer plexiform layer; INL: inner nuclear layer; IPL: inner plexiform layer; GCL: ganglion cell layer; a: sublamina a/OFF layer; b: sublamina b/ON layer.