Table 3.
Tissue | Reporter ID | Effective allele | eQTL P-value | eQTL direction | Sample size |
---|---|---|---|---|---|
Lung | 100139172_TGI_at | c | 2.6e-44 | ↓ | 1111 |
Prefrontal cortex | 10023817180 | c | 1.5e-21 | ↓ | 583 |
Visual cortex | 10023817180 | c | 4.0e-11 | ↓ | 409 |
Cerebellum | 10023817180 | c | 5.7e-12 | ↓ | 496 |
Liver | 10023817180 | c | 2.1e-23 | ↓ | 563 |
Omental fat | 10023817180 | c | 2.6e-62 | ↓ | 675 |
Subcutaneous fat | 10023817180 | c | 1.6e-29 | ↓ | 611 |
Expressional QTLs (eQTLs) between rs10553596 and CASP7 expression level were reported in large tissue collections, including lung [40], brain regions [41], liver [42] and fat tissues [42]. In lung eQTL study, Affymetrix HU133 array was used; and in other eQTL studies, Agilent Human44K1.1 array were employed