Table 2. MANF serum concentrations (ng/ml) in the study groups.

	T1D	AAB+	AAB−
Age 1–9 years
n	98	48	48
Mean ± SD	11.1 ±7.5	7.5 ±3.8	7.2 ±2.8
Median; 25%-75%	9.5; 6.2–12.9	6.1; 5.2–9.0	7.0; 5.4–8.3
Min-Max	2.3–40.1	2.2–22.8	2.9–14.9
Age 10–17 years
n	88	44	45
Mean ± SD	8.1 ±4.1	6.8 ±3.2	7.1 ±3.7
Median; 25%-75%	7.2; 5.4–9.7	6.0; 4.2–8.7	6.6; 5.0–8.7
Min-Max	2.7–19.6	2.3–14.5	1.4–21.8
Age 25–52 years
n	20	20	20
Mean ± SD	6.5 ±2.9	7.4 ±4.2	6.0 ±2.7
Median; 25%-75%	6.3; 4.3–7.2	6.5; 5.5–7.7	5.6; 3.9–8.0
Min-Max	3.1–13.7	2.3–22.3	2.7–12.3

T1D = Type 1 diabetes patients, AAB+ = autoantibody-positive non-diabetic controls, AAB− = autoantibody-negative non-diabetic controls.