Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Bioactivity of Manadomanzamines A, B and Xestomanzamine Aa
| anti-TB |
anti-HIV-1 |
antifungal IC50 (μg/mL) |
||||
|---|---|---|---|---|---|---|
| MIC (μg/mL) |
EC50
(μg/mL) |
Candida
albicans |
Cryptococcus
neoformans |
cytotoxicity IC50 (μg/mL) |
||
| compd | A-594 | H-116 | ||||
| manadomanzamine A | 1.9 | 7.0 | 20 | NA | 2.5 | 5.0 |
| manadomanzamine B | 1.5 | 16.5 | NA | 3.5 | >5 | 5.0 |
| xestomanzamine A | 14.1 | 11.2 | NA | 6.0 | >5 | >5 |
A-594 = human lung carcinoma; H-116 = human colon carcinoma; NA = not active.
